Twitterific
A downloadable application which have multiple account support, auto refreshing mechanism, audio notification of new tweets and integration with AppleScript. Compatible with Mac OS X 10.4 or later
Mad Twitter
Twitterific for Windows
Tweet-r
An Air Application that differentiates itself from other downloadable twitter applications through its flawless drag-and-drop file uploading system.
Twidget
a downloadable application with all the features of twitter except that it auto refreshes.
Twhirl
popular software that can handle multiple accounts, URL shortening, crossposting to Pownce and Jaiku, Post images on Twitpic, and search tweets using twitter search and tweetscan.
Tweetdeck
Adobe AIR application that lets you view your replies and public tweets as well as group tweets at the same time
Twinja
another twitter client built on AIR
Snitter
another twitter client built on AIR
Pwytter
A standalone Twitter client
Teletwitter
Twitter client for Windows
Twitterlicious
Twitter for Windows that supports proxies, have a read-unread system and auto-refresh mechanism.
Twitter CLI
Tweet via a command line
BLT
Another tool to update Twitter on a command line
Twitteroo
Let you send tweets on your PC with URL shortening and sound notifications for tweets
Chirrup
A Japanese software which showcases your followers and accounts in other social networks
Twadget
Twitter tool for Windows Vista
Twitgit
Twitter widget for Mac users
Vim Twitter Client
A simple client by Vim
ZenTwitter
Update Twitter without opening a window
Twitux
Another simple Twitter client
Deskbar Twitter
Update Twitter on Ubuntu
Gtwitter
Update Twitter on Linux
Twit.el
update Twitter on Emacs
Spaz
open source desktop client for Mac, Windows and Linux
Tweeter
client that is Java-based and supports proxies. Inspired by Twitteroo
GTwitter
GTwitter is a Linux client for reading and posting to twitter.com web service.
Natsulion
Simple Twitter client for Mac
Twitterpod
TwitterPod can store logs to database and search Twitter logs quickly like Mail.app
Twitterpost
TwitterPost allows you to easily post to and read from your Twitter feed - plus a whole lot more
Twittereeze
Twellow
A Twitter directory sorted by occupation
Just Tweet It
A twitter directory sorted by interest
Twubble
Twittie Me
Search for similar users and advertise your twitter page
Twitdir
Twitter Search (Summize previously)
Search for the latest trends on Twitter
Twitscoop
A search tool that tracks trends as well as certain events.
Flaptor Search
A search tool that can be installed on your browser.
Tweet Scan
Search keywords on Twitter
Twitterment
Search Twitter users and topics
Twitbuzz
Find out the latest links and conversations on Twitter
Tweetmeme
find out the latest Stories on Twitter
Twistori
Find out what twitter loves, hates, believes, etc.
Twitturly
Find out the most talked about stories on Twitter
Twitterverse
Find out what Twitter is doing
GoodBadMe
Keep track of the good and bad on the twitterverse
Favotter
Find out the most favored (saved to favorites) tweets
Twitstat
Twitterholic
Find out who the top twitter users are
Toptweet
Find out the top twitter users on one place.
Twitrank
a list of the top 150 Twitterers
Tweet Beep
Find out who is talking about you or your website through certain keywords
Site volume
Enter five keywords and see their activity on Twitter
Tweet Volume
A more personalize version of Site Volume
Monitter
Monitor Twitter conversations on three keywords. Good for catching the latest news
Hashtags
Track a certain keyword on Twitter
Twemes
See twitter memes or tags for Twitter
Tweetchannel
Find out what people are talking about through certain keywords called channels.
Twitter Meter
Find the trends of certain keywords
Flaptor Trends
Compare the trends of three keywords on Twitter
Twitter Spectrum
Find out the dominant keywords via a tagcloud generated.
Serendipitwiterrous
Search for tweets of a certain person using certain keywords
Twittertroll
Twitter Buzz
See the most popular links on Twitter
Link Bunch
Share more than one link on Twitter
Tweetwire
Sorts out links posted on Twitter into news format
Twitterlinkr
Find out the latest links posted on Twitter
Twitturls
Find out the latest URLs posted on Twitter
Twitter Split
Twittearth
Watch as people from different parts of the world tweet.
Twitter Vision
Watch Twitter in real time and see the location of Twitter users
My Tweet Map
A high tech map that tracks the location of a person
GeoTwitterous
Track a person across the map
Twitter Map
Same with GeoTwitterous
Twitter Local
Find out Tweets about a certain locale
TwitSpy
Another way where you can track the location of tweets
Geo Twitter
Another twitter location tracking site
Mibazaar
Micro Reviews
Post reviews on Twitter
Notches
Tweet Wheel
Find out which of your friends know each other
Twitter Karma
Find out who is following and unfollowing you. Have a mass follow and unfollow tool.
Twitter Snooze
If you have noisy twitter friends, you can snooze them for a certain time so you won't receive their tweets.
My Tweeple
Evaluate your followers through the number of dings (recommendations) they have from other Twitter users
Less Friends
Find out who unfollowed you using this tool
Qwitter
Receive the names of the people who unfollowed you via email.
Does Follow
Tells you if a certain follower is following a person or not
Twitterless
Receive a direct message when someone unfollows you
Twitter100
Find out the latest 100 posts of your followers
Twitterator
Follow a list of people all at once
Twitter Who
Invite lots of people in one go
Twitterlex